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Introduction Clenbuterol is an orally active, potent, and selective beta-2 adrenoceptor agonist (causes bronchodilation), used in the treatment of asthma in European countries Kamburoff et al (1977) Tschan et al (1979) Daubert et al (2007) Kamalakkannan et al (2008). Clenbuterol improved glucose tolerance after 4 days of treatment and these effects were maintained for up to 42 days. Effects were achieved with doses in a clinically relevant microgram range. Therefore, it is used therapeutically for the management of acute and chronic respiratory disorders in horses. It may also cause a reduction in release of allergic and inflammatory mediators from mast cells in the lungs. V All drugs have side effects that can affect other body functions. Clenbuterol, (RS)-1-(4-amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethan-1-ol, as C12H18Cl2N2O, molar mass 277. Characteristics make clenbuterol a therapeutically useful, orally active, β2 agonist bronchodilator (Collett et al. , 1983; Harkins et al. Beta2-agonists are often used to treat asthma. In addition to being used to treat asthma, clenbuterol has become popular as a weight loss supplement. That’s because of its effect on muscle growth. They sometimes are used as tocolytics, medications that can delay labor by relaxing the smooth muscle of the uterus. Bronchodilation Beta agonists including clenbuterol are strong bronchodilators, drugs that can increase the diameter of the airways. They accomplish this by relaxing the smooth muscle tissue of the breathing tubes

 

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